Shim-pack Scepter prep columns consist of an organosilane hybrid particle for excellent stability and performance and reliable scaleup from a Scepter HD-C18-80 analytical column. The high density C18 ligand provides increased retention and improved steric selectivity for isomers and structural analogs compared to traditional C18 phases, and is compatible with mobile phases up to pH 12. USP L1, pH range: 1-12, Max pressure: 45 MPa/450 bar/6,500 psi. 80A pore size, 25% carbon load, fully endcapped. Method development on an analytical Scepter HD-C18-80 column is highly recommended before purchasing a prep column. Prep columns cannot be returned or exchanged once used.