The Scepter Claris column has a bioinert surface treatment on the column body and frit for a completely metal-free flowpath. It is ideal for the analysis of compounds that adsorb to either stainless steel or PEEK. The organosilane hybrid particle with pentafluorophenyl ligand provides alternate selectivity to a C8 or C18, and is recommended for the analysis of aromatic and positively charged (especially N-containing) compounds. The PFPP phase can be used in reversed-phase mode with 100% aqueous conditions, or in HILIC mode for increased LCMS sensitivity. Bioinert coating eliminates adsorption and reduces tailing for compounds that have strong interactions with stainless steel or PEEK surfaces. USP L43, pore size: 120A, pH range: 1-8, max pressure: 45 MPa/450 bar/6,500 psi, 15% carbon load, non-endcapped.