Shim-pack Scepter prep columns consist of an organosilane hybrid particle for excellent stability and performance and reliable scaleup from a Scepter C18-120 analytical column. The C18 phase is a general-purpose column suitable for a wide variety of applications and mobile phase conditions up to pH 12 and 100% aqueous. USP L1, pore size: 120A, pH range: 1-12, max pressure: 45 MPa/450 bar/6,500 psi, 20% carbon load, fully endcapped. Method development on an analytical Scepter C18-120 column is highly recommended before purchasing a prep column. Prep columns cannot be returned or exchanged once used. Use with prep guard cartridges 227-31127-03 and holder 227-31171-03 to prolong the life of the column. Similar to XBridge BEH C18, XTerra C18, and Gemini C18.