Application-specific column for the analysis of NMN (Nicotinamide Mononucleotide) and related compounds in biological samples. The column hardware is a PEEK-lined stainless steel body with a high pressure polymer frit for a completely metal-free flowpath. Fully porous silica with an endcapped C18 phase. 120A pore size, 340 m2/g surface area, 13% carbon load. Maximum operating pressure: 40MPa/400 bar/6000 psi, pH range: 2 - 7.5. Maximum temperature: 80C (pH 3 or higher.)