The Shim-pack Bio Diol is a size exclusion chromatography column for proteins, nucleic acids and peptides. The 250A pore size is optimized for the analysis of size variants (aggregates and fragments) of antibody drugs. USP L20, L59. Silica based particle with a diol ligand, pH range 5-7.5, MW range 10,000 to 700,000 Da, maximum pressure 14 MPa/140 bar/2000 psi, max temp. 40C.