Nexera UC Chiral CCO F4, 5 Micron, 4.6 x 100mm The Nexera UC Chiral CCO F4 incorporates a fluoro group in its phenyl carbamate cellulose structure, which is useful in promoting fluorophilic retention mechanisms. Fluorophilic retention can be particularly useful in medicinal chemistry and drug discovery where more than a third of newly approved small molecule drugs contain fluorine. The Nexera UC Chiral CCO F4 columns are similar to CCO F2 but with a 4-fluoro 3-methylphenyl cellulose structure that can be used for SFC or HPLC.